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・ Mecano (disambiguation)
・ Mecano discography
・ Mecanoo
・ Mecanum wheel
・ Mecapaca
・ Mecapaca Municipality
・ Mecaplast Group
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・ Mecar M72
・ MeCard
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・ Mecardonia procumbens
・ Mecarobot Golf
・ Mecas
・ Mecasermin
Mecasermin rinfabate
・ Mecasoma validicornis
・ Mecaspis
・ Mecaspis alternans
・ Mecate
・ Mecate (band)
・ Mecate rein
・ Mecatepe Lagoon Natural Reserve
・ Mecatina
・ Mecatlán
・ Mecaya River
・ Mecayapan
・ MECC
・ MECC (disambiguation)
・ Mecc Alte


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Mecasermin rinfabate : ウィキペディア英語版
Mecasermin rinfabate

Mecasermin rinfabate (trade name iPlex) is a drug consisting of recombinant Insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3).
It is believed to be similar in effect to mecasermin, but with fewer side effects (such as hypoglycemia).
==Potential uses==
It was developed by INSMED corporation for the treatment of growth failure in children with severe primary IGF-I deficiency (Primary IGFD) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH. Due to a patent settlement, IPLEX is being taken off the market for short stature related indications. However, IPLEX is being studied as a treatment for other several serious medical conditions.
On March 11, 2009 the FDA announced that mecasermin rinfabate would be made available to Americans with amyotrophic lateral sclerosis, more commonly known as Lou Gehrig's disease, as a part of a clinical trial. The drug is currently available in Italy for this condition.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Mecasermin rinfabate」の詳細全文を読む



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